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The influence of interleukin-7 receptor ?-chain haplotypes on outcome after allogeneic hematopoietic cell transplantation.

ABSTRACT: We investigated the influence of IL-7 receptor ?-chain (IL-7R?) gene haplotypes in donors on the outcome of haematopoietic cell transplantation (HCT). Unlike the association between single donor SNPs and HCT outcome found previously, only trends towards association were found here, due to 'dilution' of SNPs into haplotypes.

SUBMITTER: Broux B 

PROVIDER: S-EPMC4238034 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature

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The influence of interleukin-7 receptor α-chain haplotypes on outcome after allogeneic hematopoietic cell transplantation.

Broux B B   Shamim Z Z   Wang T T   Spellman S S   Haagenson M M   Stinissen P P   Ryder L P LP   Müller K K   Hellings N N  

International journal of immunogenetics 20141029 6

We investigated the influence of IL-7 receptor α-chain (IL-7Rα) gene haplotypes in donors on the outcome of haematopoietic cell transplantation (HCT). Unlike the association between single donor SNPs and HCT outcome found previously, only trends towards association were found here, due to 'dilution' of SNPs into haplotypes. ...[more]

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