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Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.

ABSTRACT: High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved. These domains were chosen as targets of a biomedical theme project pursued by the Northeast Structural Genomics Consortium. This project focuses on increasing the structural coverage of human proteins associated with cancer.

SUBMITTER: Xu X

PROVIDER: S-EPMC4239167 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature

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Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.

Xu Xianzhong X Pulavarti Surya V S R K SV Eletsky Alexander A Huang Yuanpeng Janet YJ Acton Thomas B TB Xiao Rong R Everett John K JK Montelione Gaetano T GT Szyperski Thomas T

Journal of structural and functional genomics 20140619 4

High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved. These domains were chosen as targets of a biomedical theme project pursued by the Northeast Structural Genomics Consortium. This project focuses on increasing the structural coverage of human proteins associated with cancer. ...[more]

PMID: 24941917

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