Ontology highlight
ABSTRACT:
SUBMITTER: Xie L
PROVIDER: S-EPMC4239420 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Xie Lan L Mouillet Jean-Francois JF Chu Tianjiao T Parks W Tony WT Sadovsky Elena E Knöfler Martin M Sadovsky Yoel Y
Endocrinology 20140911 12
Early in pregnancy, trophoblast invasion into the decidua and inner myometrium is essential for establishment of proper implantation, maternal-fetal exchange, and immunological tolerance of the feto-placental allograft. Unlike villous trophoblasts (VTs), extravillous trophoblasts (EVTs) are unique in their capacity to invade the maternal decidua and myometrium. The largest human microRNA (miRNA) gene cluster, the chromosome 19 miRNA cluster (C19MC), is expressed almost exclusively in the placent ...[more]