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Hepatic actinomycosis: report of one case and analysis of 32 previously reported cases.

ABSTRACT: Hepatic actinomycosis is rare, with few published cases. There are no characteristic clinical manifestations, and computed tomography (CT) shows mainly low-density images, making clinical diagnosis difficult, and leading to frequent misdiagnosis as primary liver cancer, metastatic liver cancer or liver abscess. Diagnosis normally requires examination of both the aetiology and pathology. This article reports one male patient aged 55 who was hospitalized because of repeated upper abdominal pain for more than 2 mo. He exhibited no chills, fever or yellow staining of the skin and sclera, and examination revealed no positive signs. The routine blood results were: haemoglobin 110 g/L, normal numbers of leukocytes and neutral leukocytes, serum albumin 32 g/L, negative serum hepatitis B markers and hepatitis C antibodies, normal tumour markers (alpha-fetoprotein and carcinoembryonic antigen). An abdominal CT scan revealed an 11.2 cm × 5.8 cm × 7.4 cm mass with an unclear edge in the left liver lobe. The patient was diagnosed as having primary liver cancer, and left lobe resection was performed. The postoperative pathological examination found multifocal actinomycetes in the hepatic parenchyma, which was accompanied by chronic suppurative inflammation. A focal abscess had formed, and large doses of sodium penicillin were administered postoperatively as anti-infective therapy. This article also reviews 32 cases reported in the English literature, with the aim of determining the clinical features and treatment characteristics of this disease, and providing a reference for its diagnosis and treatment.

SUBMITTER: Yang XX

PROVIDER: S-EPMC4239533 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature

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Hepatic actinomycosis: report of one case and analysis of 32 previously reported cases.

Yang Xing-Xiang XX Lin Jian-Mei JM Xu Kai-Ju KJ Wang Shu-Qiang SQ Luo Ting-Ting TT Geng Xiao-Xia XX Huang Ren-Gang RG Jiang Nan N

World journal of gastroenterology 20141101 43

Hepatic actinomycosis is rare, with few published cases. There are no characteristic clinical manifestations, and computed tomography (CT) shows mainly low-density images, making clinical diagnosis difficult, and leading to frequent misdiagnosis as primary liver cancer, metastatic liver cancer or liver abscess. Diagnosis normally requires examination of both the aetiology and pathology. This article reports one male patient aged 55 who was hospitalized because of repeated upper abdominal pain fo ...[more]

PMID: 25473199

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Dataset Information

Hepatic actinomycosis: report of one case and analysis of 32 previously reported cases.

Publications

Hepatic actinomycosis: report of one case and analysis of 32 previously reported cases.

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