Ontology highlight
ABSTRACT:
SUBMITTER: Merchant ML
PROVIDER: S-EPMC4241022 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Merchant Michael L ML Niewczas Monika A MA Ficociello Linda H LH Lukenbill Janice A JA Wilkey Daniel W DW Li Ming M Khundmiri Syed J SJ Warram James H JH Krolewski Andrzej S AS Klein Jon B JB
Kidney international 20130306 6
The ability of microalbuminuria to predict early progressive renal function decline in type 1 diabetic patients has been questioned. To resolve this, we determined the plasma proteome differences between microalbuminuric patients with type 1 diabetes and stable renal function (controls) and patients at risk for early progressive renal function decline (cases) and asked whether these differences have value as surrogate biomarkers. Mass spectrometry was used to analyze small (<3 kDa) plasma peptid ...[more]