Ontology highlight
ABSTRACT:
SUBMITTER: Deangelis MM
PROVIDER: S-EPMC4242505 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Deangelis Margaret M MM Silveira Alexandra C AC Carr Elizabeth A EA Kim Ivana K IK
Seminars in ophthalmology 20110501 3
Age-related macular degeneration (AMD) is a progressive degenerative disease which leads to blindness, affecting the quality of life of millions of Americans. More than 1.75 million individuals in the United States are affected by the advanced form of AMD. The etiological pathway of AMD is not yet fully understood, but there is a clear genetic influence on disease risk. To date, the 1q32 (CFH) and 10q26 (PLEKHA1/ARMS2/HTRA1) loci are the most strongly associated with disease; however, the variat ...[more]