Ontology highlight
ABSTRACT:
SUBMITTER: Ming L
PROVIDER: S-EPMC4245531 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Ming Leiguo L Jin Fang F Huang Ping P Luo Hailang H Liu Wenjia W Zhang Leilei L Yuan Wei W Zhang Yongjie Y Jin Yan Y
Scientific reports 20141127
The role of bone marrow-derived mesenchymal stem cells(BMSCs)in the pathogenesis and therapy of osteoporosis has drawn increasing attention in recent years. In the development of osteoporosis, it has been demonstrated that many changes occurred in the behavior of BMSCs. For example, the biological system of FasL pathways mediated differentiation of ERK and GSK-3β-catenin pathway was damaged. Here we found that 0.35 mg/L Licochalcone A (L-A) had a strong effect in increasing the osteogenic differ ...[more]