Ontology highlight
ABSTRACT:
SUBMITTER: Dankova V
PROVIDER: S-EPMC4249281 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Dankova Vera V Balonova Lucie L Straskova Adela A Spidlova Petra P Putzova Daniela D Kijek Todd T Bozue Joel J Cote Christopher C Mou Sherry S Worsham Patricia P Szotakova Barbora B Cerveny Lukas L Stulik Jiri J
Infection and immunity 20140922 12
Francisella tularensis is a highly infectious bacterium that causes the potentially lethal disease tularemia. This extremely virulent bacterium is able to replicate in the cytosolic compartments of infected macrophages. To invade macrophages and to cope with their intracellular environment, Francisella requires multiple virulence factors, which are still being identified. Proteins containing tetratricopeptide repeat (TPR)-like domains seem to be promising targets to investigate, since these prot ...[more]