Cortical thickness, surface area and volume measures in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy.
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ABSTRACT:
SUBMITTER: Worker A
PROVIDER: S-EPMC4252086 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Cortical thickness, surface area and volume measures in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy.
Worker Amanda A Blain Camilla C Jarosz Jozef J Chaudhuri K Ray KR Barker Gareth J GJ Williams Steven C R SC Brown Richard R Leigh P Nigel PN Simmons Andrew A
PloS one 20141202 12
<h4>Objective</h4>Parkinson's disease (PD), Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP) are neurodegenerative diseases that can be difficult to distinguish clinically. The objective of the current study was to use surface-based analysis techniques to assess cortical thickness, surface area and grey matter volume to identify unique morphological patterns of cortical atrophy in PD, MSA and PSP and to relate these patterns of change to disease duration and clinical featur ...[more]
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