Ontology highlight
ABSTRACT:
SUBMITTER: Kakourou A
PROVIDER: S-EPMC4253302 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Kakourou Alexia A Vach Werner W Mertens Bart B
Journal of computational biology : a journal of computational molecular cell biology 20141201 12
We consider a proteomic mass spectrometry case-control study for the construction of a diagnostic rule for patients' disease status allocation. We propose an approach for combining a collection of classifiers for the construction of a "combined" classification rule in order to enhance calibration and prediction ability. In a first stage this is achieved by building individual classifiers separately, each one using the entire proteomic data set. A double leave-one-out cross-validatory approach is ...[more]