Direct interaction of actin filaments with F-BAR protein pacsin2.
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ABSTRACT:
SUBMITTER: Kostan J
PROVIDER: S-EPMC4253489 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Publications
Direct interaction of actin filaments with F-BAR protein pacsin2.
Kostan Julius J Salzer Ulrich U Orlova Albina A Törö Imre I Hodnik Vesna V Senju Yosuke Y Zou Juan J Schreiner Claudia C Steiner Julia J Meriläinen Jari J Nikki Marko M Virtanen Ismo I Carugo Oliviero O Rappsilber Juri J Lappalainen Pekka P Lehto Veli-Pekka VP Anderluh Gregor G Egelman Edward H EH Djinović-Carugo Kristina K
EMBO reports 20140912 11
Two mechanisms have emerged as major regulators of membrane shape: BAR domain-containing proteins, which induce invaginations and protrusions, and nuclear promoting factors, which cause generation of branched actin filaments that exert mechanical forces on membranes. While a large body of information exists on interactions of BAR proteins with membranes and regulatory proteins of the cytoskeleton, little is known about connections between these two processes. Here, we show that the F-BAR domain ...[more]
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