Ontology highlight
ABSTRACT:
SUBMITTER: DeVylder JE
PROVIDER: S-EPMC4254175 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
DeVylder Jordan E JE Muchomba Felix M FM Gill Kelly E KE Ben-David Shelly S Walder Deborah J DJ Malaspina Dolores D Corcoran Cheryl M CM
Schizophrenia research 20140919 2-3
<h4>Background</h4>Prior studies have implicated baseline positive and negative symptoms as predictors of psychosis onset among individuals at clinical high risk (CHR), but none have evaluated latent trajectories of symptoms over time. This study evaluated the dynamic evolution of symptoms leading to psychosis onset in a CHR cohort.<h4>Method</h4>100 CHR participants were assessed quarterly for up to 2.5 years. Latent trajectory analysis was used to identify patterns of symptom change. Logistic ...[more]