Ontology highlight
ABSTRACT:
SUBMITTER: Siebrasse EA
PROVIDER: S-EPMC4254350 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Siebrasse Erica A EA Nguyen Nang L NL Smith Colin C Simmonds Peter P Wang David D
Virology 20140903
Little is known about the tissue tropism of KI polyomavirus (KIPyV), and there are no studies to date describing any specific cell types it infects. The limited knowledge of KIPyV tropism has hindered study of this virus and understanding of its potential pathogenesis in humans. We describe tissues from two immunocompromised patients that stained positive for KIPyV antigen using a newly developed immunohistochemical assay targeting the KIPyV VP1 (KVP1) capsid protein. In the first patient, a ped ...[more]