Ontology highlight
ABSTRACT:
SUBMITTER: Viscoli CM
PROVIDER: S-EPMC4254508 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Viscoli Catherine M CM Brass Lawrence M LM Carolei Antonio A Conwit Robin R Ford Gary A GA Furie Karen L KL Gorman Mark M Guarino Peter D PD Inzucchi Silvio E SE Lovejoy Anne M AM Parsons Mark W MW Peduzzi Peter N PN Ringleb Peter A PA Schwartz Gregory G GG Spence J David JD Tanne David D Young Lawrence H LH Kernan Walter N WN
American heart journal 20140728 6
<h4>Background</h4>Recurrent vascular events remain a major source of morbidity and mortality after stroke or transient ischemic attack (TIA). The IRIS Trial is evaluating an approach to secondary prevention based on the established association between insulin resistance and increased risk for ischemic vascular events. Specifically, IRIS will test the effectiveness of pioglitazone, an insulin-sensitizing drug of the thiazolidinedione class, for reducing the risk for stroke and myocardial infarct ...[more]