Ontology highlight
ABSTRACT:
SUBMITTER: Nolivos S
PROVIDER: S-EPMC4255302 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Nolivos Sophie S Sherratt David D
FEMS microbiology reviews 20131118 3
Structural Maintenance of Chromosomes (SMC) protein complexes are found in all three domains of life. They are characterized by a distinctive and conserved architecture in which a globular ATPase 'head' domain is formed by the N- and C-terminal regions of the SMC protein coming together, with a c. 50-nm-long antiparallel coiled-coil separating the head from a dimerization 'hinge'. Dimerization gives both V- and O-shaped SMC dimers. The distinctive architecture points to a conserved biochemical m ...[more]