Ontology highlight
ABSTRACT:
SUBMITTER: Jiang F
PROVIDER: S-EPMC4255559 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Jiang Feng F Qiu Qi Q Khanna Abha A Todd Nevins W NW Deepak Janaki J Xing Lingxiao L Wang Huijun H Liu Zhenqiu Z Su Yun Y Stass Sanford A SA Katz Ruth L RL
Molecular cancer research : MCR 20090310 3
Tumor contains small population of cancer stem cells (CSC) that are responsible for its maintenance and relapse. Analysis of these CSCs may lead to effective prognostic and therapeutic strategies for the treatment of cancer patients. We report here the identification of CSCs from human lung cancer cells using Aldefluor assay followed by fluorescence-activated cell sorting analysis. Isolated cancer cells with relatively high aldehyde dehydrogenase 1 (ALDH1) activity display in vitro features of C ...[more]