Ontology highlight
ABSTRACT:
SUBMITTER: Han X
PROVIDER: S-EPMC4256133 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Proteins 20141118 1
Octaprenyl pyrophosphate synthase (OPPs) catalyzes consecutive condensation reactions of one allylic substrate farnesyl pyrophosphate (FPP) and five homoallylic substrate isopentenyl pyrophosphate (IPP) molecules to form a C40 long-chain product OPP, which serves as a side chain of ubiquinone and menaquinone. OPPs belongs to the trans-prenyltransferase class of proteins. The structures of OPPs from Escherichia coli were solved in the apo-form as well as in complexes with IPP and a FPP thio-analo ...[more]