Casting inorganic structures with DNA molds.
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ABSTRACT:
SUBMITTER: Sun W
PROVIDER: S-EPMC4260265 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Publications
Casting inorganic structures with DNA molds.
Sun Wei W Boulais Etienne E Hakobyan Yera Y Wang Wei Li WL Guan Amy A Bathe Mark M Yin Peng P
Science (New York, N.Y.) 20141009 6210
We report a general strategy for designing and synthesizing inorganic nanostructures with arbitrarily prescribed three-dimensional shapes. Computationally designed DNA strands self-assemble into a stiff "nanomold" that contains a user-specified three-dimensional cavity and encloses a nucleating gold "seed." Under mild conditions, this seed grows into a larger cast structure that fills and thus replicates the cavity. We synthesized a variety of nanoparticles with 3-nanometer resolution: three dis ...[more]
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