Characterization of the cellular localization of C4orf34 as a novel endoplasmic reticulum resident protein.
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ABSTRACT:
SUBMITTER: Jun MH
PROVIDER: S-EPMC4261514 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Publications
Characterization of the cellular localization of C4orf34 as a novel endoplasmic reticulum resident protein.
Jun Mi-Hee MH Jun Young-Wu YW Kim Kun-Hyung KH Lee Jin-A JA Jang Deok-Jin DJ
BMB reports 20141001 10
Human genome projects have enabled whole genome mapping and improved our understanding of the genes in humans. However, many unknown genes remain to be functionally characterized. In this study, we characterized human chromosome 4 open reading frame 34 gene (hC4orf34). hC4orf34 was highly conserved from invertebrate to mammalian cells and ubiquitously expressed in the organs of mice, including the heart and brain. Interestingly, hC4orf34 is a novel ER-resident, type I transmembrane protein. Muta ...[more]
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