Ontology highlight
ABSTRACT:
SUBMITTER: Hyun H
PROVIDER: S-EPMC4267294 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Hyun Hoon H Owens Eric A EA Narayana Lakshminarayana L Wada Hideyuki H Gravier Julien J Bao Kai K Frangioni John V JV Choi Hak Soo HS Henary Maged M
RSC advances 20140101 102
Functional near-infrared (NIR) fluorophores have played a major role in the recent advances in bioimaging. However, the optical and physicochemical stabilities of NIR fluorophores in the biological and physiological environment are still a challenge. Especially, the ether linkage on the <i>meso</i> carbon of heptamethine core is fragile when exposed to serum proteins or other amine-rich biomolecules. To solve such a structural limitation, a rigid carbon-carbon bond was installed onto the framewo ...[more]