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Dehalogenation of Functionalized Alkyl Halides in Water at Room Temperature.

ABSTRACT: Alkyl bromides and chlorides can be reduced to the corresponding hydrocarbons utilizing zinc in the presence of an amine additive. The process takes place in water at ambient temperatures, enabled by a commercially available designer surfactant. The reaction medium can be readily recycled, and the amount of organic solvent invested for product isolation is minimal, leading to very low E Factors.

SUBMITTER: Isley NA

PROVIDER: S-EPMC4267473 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Dehalogenation of Functionalized Alkyl Halides in Water at Room Temperature.

Isley Nicholas A NA Hageman Matt S MS Lipshutz Bruce H BH

Green chemistry : an international journal and green chemistry resource : GC 20150101

Alkyl bromides and chlorides can be reduced to the corresponding hydrocarbons utilizing zinc in the presence of an amine additive. The process takes place in water at ambient temperatures, enabled by a commercially available designer surfactant. The reaction medium can be readily recycled, and the amount of organic solvent invested for product isolation is minimal, leading to very low E Factors. ...[more]

PMID: 25530711

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