Ontology highlight
ABSTRACT:
SUBMITTER: Kurani AS
PROVIDER: S-EPMC4268125 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Kurani Ajay S AS Seidler Rachael D RD Burciu Roxana G RG Comella Cynthia L CL Corcos Daniel M DM Okun Michael S MS MacKinnon Colum D CD Vaillancourt David E DE
Neurobiology of aging 20140711 1
Previous research has indicated increased functional connectivity between subthalamic nucleus (STN) and sensorimotor cortex in off-medication Parkinson's disease (PD) compared with control subjects. It is not clear if the increase in functional connectivity between STN and sensorimotor cortex occurs in de novo PD, which is before patients begin dopamine therapy. Resting-state functional magnetic resonance imaging was carried out in 20 de novo (drug naïve) patients with PD (Hoehn and Yahr stage: ...[more]