Ontology highlight
ABSTRACT:
SUBMITTER: Abdel-Latif A
PROVIDER: S-EPMC4270753 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Abdel-Latif Ahmed A Zuba-Surma Ewa K EK Case Jamie J Tiwari Sumit S Hunt Greg G Ranjan Smita S Vincent Robert J RJ Srour Edward F EF Bolli Roberto R Dawn Buddhadeb B
Basic research in cardiology 20080523 6
The optimal medium for cardiac differentiation of adult primitive cells remains to be established. We quantitatively compared the efficacy of IGF-1, dynorphin B, insulin, oxytocin, bFGF, and TGF-beta1 in inducing cardiomyogenic differentiation. Adult mouse skeletal muscle-derived Sca1+/CD45-/c-kit-/Thy-1+ (SM+) and Sca1-/CD45-/c-kit-/Thy-1+ (SM-) cells were cultured in basic medium (BM; DMEM, FBS, IGF-1, dynorphin B) alone and BM supplemented with insulin, oxytocin, bFGF, or TGF-beta1. Cardiac d ...[more]