Ontology highlight
ABSTRACT:
SUBMITTER: Bendjilali N
PROVIDER: S-EPMC4271021 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Bendjilali Nasrine N Hsueh Wen-Chi WC He Qimei Q Willcox D Craig DC Nievergelt Caroline M CM Donlon Timothy A TA Kwok Pui-Yan PY Suzuki Makoto M Willcox Bradley J BJ
The journals of gerontology. Series A, Biological sciences and medical sciences 20140120 12
Isolated populations have advantages for genetic studies of longevity from decreased haplotype diversity and long-range linkage disequilibrium. This permits smaller sample sizes without loss of power, among other utilities. Little is known about the genome of the Okinawans, a potential population isolate, recognized for longevity. Therefore, we assessed genetic diversity, structure, and admixture in Okinawans, and compared this with Caucasians, Chinese, Japanese, and Africans from HapMap II, gen ...[more]