Ontology highlight
ABSTRACT:
SUBMITTER: Malik MQ
PROVIDER: S-EPMC4271232 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Malik Mariam Q MQ Bertke Michelle M MM Huber Paul W PW
The Journal of biological chemistry 20141103 51
The 5 S rRNA gene-specific transcription factor IIIA (TFIIIA) interacts with the small ubiquitin-like modifier (SUMO) E3 ligase PIAS2b and with one of its targets, the transcriptional corepressor, XCtBP. PIAS2b is restricted to the cytoplasm of Xenopus oocytes but relocates to the nucleus immediately after fertilization. Following the midblastula transition, PIAS2b and XCtBP are present on oocyte-type, but not somatic-type, 5 S rRNA genes up through the neurula stage, as is a limiting amount of ...[more]