Ontology highlight
ABSTRACT:
SUBMITTER: Nichols CM
PROVIDER: S-EPMC4272371 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Nichols Claire M CM Povstyan Oleksandr V OV Albert Anthony P AP Gordienko Dmitry V DV Khan Omar O Vasilikostas Georgios G Khong Teck K TK Wan Andrew A Reddy Marcus M Harhun Maksym I MI
Purinergic signalling 20140522 4
Stimulation of P2X receptors by ATP in vascular smooth muscle cells (VSMCs) is proposed to mediate vascular tone. However, understanding of P2X receptor-mediated actions in human blood vessels is limited, and therefore, the current work investigates the role of P2X receptors in freshly isolated small human gastro-omental arteries (HGOAs). Expression of P2X1 and P2X4 receptor subunit messenger RNA (mRNA) and protein was identified in individual HGOA VSMCs using RT-PCR and immunofluorescent analys ...[more]