Ontology highlight
ABSTRACT:
SUBMITTER: Argo CK
PROVIDER: S-EPMC4272639 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Argo Curtis K CK Patrie James T JT Lackner Carolin C Henry Thomas D TD de Lange Eduard E EE Weltman Arthur L AL Shah Neeral L NL Al-Osaimi Abdullah M AM Pramoonjago Patcharin P Jayakumar Saumya S Binder Lukas P LP Simmons-Egolf Winsor D WD Burks Sandra G SG Bao Yongde Y Taylor Ann Gill AG Rodriguez Jessica J Caldwell Stephen H SH
Journal of hepatology 20140906 1
<h4>Background & aims</h4>This study's aim was to assess the histological and metabolic effects of n-3 polyunsaturated fatty acids (PUFAs) vs. placebo while adjusting for the impact of age and weight change in NASH patients. (ClinicalTrials.gov: NCT00681408).<h4>Methods</h4>Forty-one subjects with non-cirrhotic NASH were enrolled, and 34 completed the study. 17 received n-3 fish oil 3000 mg/day and 17 received placebo daily for 1 year with typical counselling on caloric intake and physical activ ...[more]