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Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4.

ABSTRACT: The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates. Thioglycosides and glycosyl trichloroacetimidate derivatives have been used as glycosyl donors in the glycosylations.

SUBMITTER: Mandal PK

PROVIDER: S-EPMC4273275 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4.

Mandal Pintu Kumar PK

Beilstein journal of organic chemistry 20141120

The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates. Thioglycosides and glycosyl trichloroacetimidate derivatives have been used as glycosyl donors in the glycosylations. ...[more]

PMID: 25550736

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