Overexpression of PrPc, combined with MGr1-Ag/37LRP, is predictive of poor prognosis in gastric cancer.
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ABSTRACT:
SUBMITTER: Zhou L
PROVIDER: S-EPMC4277329 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
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Overexpression of PrPc, combined with MGr1-Ag/37LRP, is predictive of poor prognosis in gastric cancer.
Zhou Lin L Shang Yulong Y Liu Changhao C Li Jinge J Hu Hao H Liang Cong C Han Yanan Y Zhang Wei W Liang Jie J Wu Kaichun K
International journal of cancer 20140417 10
Prion protein (PrPc) has been previously reported to be involved in gastric cancer (GC) development and progression. However, the association between expression of PrPc and GC prognosis is yet poorly characterized. In the present study, the expressions of PrPc and MGr1-Ag/37LRP, a protein interacting with PrPc, were detected using the tissue microarray technique and immunohistochemical method to compare clinicopathological parameters of 238 GC patients. We found that the expressions of PrPc and ...[more]
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