Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC4278078 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Wang Yuting Y Sun Lei L Du Weina W Song Shuang S Wang Shuo S Jiang Weiju W Huang Tianchu T Li Hui H
Genetic testing and molecular biomarkers 20150101 1
The purpose of this study is to investigate the association of methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms with the risk of congenital heart diseases (CHD). The genotypes of the MTHFR genetic variant were determined by the polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing methods. Our data suggested that the allelic and genotypic frequencies of CHD patients were significantly different from non-CHD controls. The MTHFR c.1625A>C genetic varia ...[more]