Melanocytes in the skin--comparative whole transcriptome analysis of main skin cell types.
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ABSTRACT:
SUBMITTER: Reemann P
PROVIDER: S-EPMC4278762 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Melanocytes in the skin--comparative whole transcriptome analysis of main skin cell types.
Reemann Paula P Reimann Ene E Ilmjärv Sten S Porosaar Orm O Silm Helgi H Jaks Viljar V Vasar Eero E Kingo Külli K Kõks Sulev S
PloS one 20141229 12
Melanocytes possess several functions besides a role in pigment synthesis, but detailed characteristics of the cells are still unclear. We used whole transcriptome sequencing (RNA-Seq) to assess differential gene expression of cultivated normal human melanocytes with respect to keratinocytes, fibroblasts and whole skin. The present results reveal cultivated melanocytes as highly proliferative cells with possible stem cell-like properties. The enhanced readiness to regenerate makes melanocytes th ...[more]
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