Economic evaluation of endoscopic sinus surgery versus continued medical therapy for refractory chronic rhinosinusitis.

ABSTRACT:

Objectives/hypothesis

To evaluate the long-term cost-effectiveness of endoscopic sinus surgery (ESS) compared to continued medical therapy for patients with refractory chronic rhinosinusitis (CRS).

Study design

Cohort-style Markov decision-tree economic evaluation.

Methods

The economic perspective was the U.S. third-party payer with a 30-year time horizon. The two comparative treatment strategies were: 1) ESS, followed by appropriate postoperative medical therapy; and 2) continued medical therapy alone. Primary outcome was the incremental cost per quality-adjusted life year (QALY). Costs were discounted at a rate of 3.5% in the reference case. Multiple sensitivity analyses were performed, including differing time-horizons, discounting scenarios, and a probabilistic se

SUBMITTER: Rudmik L 

PROVIDER: S-EPMC4280303 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature