Ontology highlight
ABSTRACT:
SUBMITTER: Langefeld CD
PROVIDER: S-EPMC4281289 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Langefeld Carl D CD Divers Jasmin J Pajewski Nicholas M NM Hawfield Amret T AT Reboussin David M DM Bild Diane E DE Kaysen George A GA Kimmel Paul L PL Raj Dominic S DS Ricardo Ana C AC Wright Jackson T JT Sedor John R JR Rocco Michael V MV Freedman Barry I BI
Kidney international 20140716 1
Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin:creatinine ratio (UACR), and prevalent cardiovascular disease (CVD) in 2571 AAs from the Systolic Blood Pressure Intervention Trial (SPRINT), a trial assessing effects of systolic blood pressure reduction on renal and CVD outcomes. Logistic regressio ...[more]