Ontology highlight
ABSTRACT:
SUBMITTER: Peter BM
PROVIDER: S-EPMC4282923 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Peter Benjamin M BM Slatkin Montgomery M
Evolution; international journal of organic evolution 20130827 11
We propose a method that uses genetic data to test for the occurrence of a recent range expansion and to infer the location of the origin of the expansion. We introduce a statistic ψ (the directionality index) that detects asymmetries in the 2D allele frequency spectrum of pairs of population. These asymmetries are caused by the series of founder events that happen during an expansion and they arise because low frequency alleles tend to be lost during founder events, thus creating clines in the ...[more]