Ontology highlight
ABSTRACT:
SUBMITTER: Markt SC
PROVIDER: S-EPMC4282953 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Markt Sarah C SC Valdimarsdottir Unnur A UA Shui Irene M IM Sigurdardottir Lara G LG Rider Jennifer R JR Tamimi Rulla M RM Batista Julie L JL Haneuse Sebastien S Flynn-Evans Erin E Lockley Steven W SW Czeisler Charles A CA Stampfer Meir J MJ Launer Lenore L Harris Tamara T Smith Albert Vernon AV Gudnason Vilmundur V Lindstrom Sara S Kraft Peter P Mucci Lorelei A LA
Cancer causes & control : CCC 20141112 1
<h4>Purpose</h4>Circadian genes may be involved in regulating cancer-related pathways, including cell proliferation, DNA damage response, and apoptosis. We aimed to assess the role of genetic variation in core circadian rhythm genes with the risk of fatal prostate cancer and first morning void urinary 6-sulfatoxymelatonin levels.<h4>Methods</h4>We used unconditional logistic regression to evaluate the association of 96 single-nucleotide polymorphisms (SNPs) across 12 circadian-related genes with ...[more]