Ontology highlight
ABSTRACT:
SUBMITTER: Lotrich FE
PROVIDER: S-EPMC4284141 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Inflammatory cytokines can sometimes trigger depression in humans, are often associated with depression, and can elicit some behaviors in animals that are homologous to major depression. Moreover, these cytokines can affect monoaminergic and glutamatergic systems, supporting an overlapping pathoetiology with major depression. This suggests that there could be a specific major depression subtype, inflammatory cytokine-associated depression (ICAD), which may require different therapeutic approache ...[more]