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Orientation in multi-layer chitosan hydrogel: morphology, mechanism, and design principle.

ABSTRACT: Hydrogels with organized structure have attracted remarkable attentions for bio-related applications. Among the preparation of hierarchical hydrogel materials, fabrication of hydrogel with multi-layers is an important branch. Although the generation mechanism of layers had been fully discussed, sub-layer structure was not sufficiently studied. In this research, multi-layered chitosan hydrogel with oriented structure was constructed, and the formation mechanism of orientation was proposed, based on gelation behavior and entanglement of polymer chains in the hydrogel-solution system. Employing the layered-oriented characteristic, chitosan hydrogel materials with various shapes and structure can be designed and fabricated.

SUBMITTER: Nie J

PROVIDER: S-EPMC4284508 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

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Orientation in multi-layer chitosan hydrogel: morphology, mechanism, and design principle.

Nie Jingyi J Lu Wentao W Ma Jianjun J Yang Ling L Wang Zhengke Z Qin An A Hu Qiaoling Q

Scientific reports 20150106

Hydrogels with organized structure have attracted remarkable attentions for bio-related applications. Among the preparation of hierarchical hydrogel materials, fabrication of hydrogel with multi-layers is an important branch. Although the generation mechanism of layers had been fully discussed, sub-layer structure was not sufficiently studied. In this research, multi-layered chitosan hydrogel with oriented structure was constructed, and the formation mechanism of orientation was proposed, based ...[more]

PMID: 25559867

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