Ontology highlight
ABSTRACT:
SUBMITTER: Almutairi MS
PROVIDER: S-EPMC4284725 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Almutairi Maha S MS Hegazy Gehan H GH Haiba Mogedda E ME Ali Hamed I HI Khalifa Nagy M NM Soliman Abd El-mohsen M Ael-M
International journal of molecular sciences 20141205 12
Herein, novel hybrid compounds of celecoxib and 2-aminoanthraquinone derivatives have been synthesized using condensation reactions of celecoxib with 2-aminoanthraquinone derivatives or 2-aminoanthraquinon with celecoxib derivatives. Celecoxib was reacted with different acid chlorides, 2-chloroethylisocyanate and bis (2-chloroethyl) amine hydrochloride. These intermediates were then reacted with 2-aminoanthraquinone. Also the same different acid chlorides and 2-chloroethylisocyanate were reacted ...[more]