Ontology highlight
ABSTRACT:
SUBMITTER: Dandapani S
PROVIDER: S-EPMC4284946 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Dandapani Sivaraman S Lowe Jason T JT Comer Eamon E Marcaurelle Lisa A LA
The Journal of organic chemistry 20110829 19
An efficient build/couple/pair approach to diversity-oriented synthesis was employed to access several structurally complex macrolactams. In this paper, we describe the successful evaluation of ring-closing metathesis toward the systematic generation of skeletal diversity. By appropriately varying the nature and chain length of the alkenol fragment, a diverse collection of 13- to 18-membered macrolactams were obtained. ...[more]