Enlight: web-based integration of GWAS results with biological annotations.
Ontology highlight
ABSTRACT:
SUBMITTER: Guo Y
PROVIDER: S-EPMC4287951 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Publications
Enlight: web-based integration of GWAS results with biological annotations.
Guo Yunfei Y Conti David V DV Wang Kai K
Bioinformatics (Oxford, England) 20140926 2
<h4>Unlabelled</h4>Identifying causal variants remains a key challenge in post-GWAS (genome-wide association study) era, as many GWAS single-nucleotide polymorphisms (SNPs) (including imputed ones) fall into non-coding regions, making it difficult to associate statistical significance with predicted functionality. Therefore, we created a web-based tool, Enlight, which overlays functional annotation information, such as histone modification states, methylation patterns, transcription factor bindi ...[more]
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