Ontology highlight
ABSTRACT:
SUBMITTER: Bahrami-Samani E
PROVIDER: S-EPMC4288180 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Bahrami-Samani Emad E Penalva Luiz O F LO Smith Andrew D AD Uren Philip J PJ
Nucleic acids research 20141210 1
High-throughput protein-RNA interaction data generated by CLIP-seq has provided an unprecedented depth of access to the activities of RNA-binding proteins (RBPs), the key players in co- and post-transcriptional regulation of gene expression. Motif discovery forms part of the necessary follow-up data analysis for CLIP-seq, both to refine the exact locations of RBP binding sites, and to characterize them. The specific properties of RBP binding sites, and the CLIP-seq methods, provide additional in ...[more]