Dataset Information

Alcohol-induced changes in conflict monitoring and error detection as predictors of alcohol use in late adolescence.

ABSTRACT: Adolescence is a vulnerable period for the development of substance use and related problems. Understanding how exposure to drugs influences the adolescent brain could reveal mechanisms underlying risk for addiction later in life. In the current study, 87 adolescents (16-20-year olds; the local legal drinking age was16, allowing the inclusion of younger subjects than usually possible) underwent EEG measurements during a Go/No-Go task with and without alcohol cues; after placebo and a low dose of alcohol (0.45?g/kg). Conflict monitoring and error detection processes were investigated with the N2 and the error-related negativity (ERN) ERP components. Participants were followed-up after 6 months to assess changes in alcohol use. The NoGo-N2 was larger for alcohol cues and acute alcohol decreased the amplitude of the NoGo-N2 for alcohol cues. ERN amplitude was blunted for alcohol cues. Acute alcohol decreased the amplitude of the ERN, specifically for control cues. Furthermore, the differences in ERN for alcohol cues between the placebo and alcohol conditions predicted alcohol use 6 months later: subjects who showed stronger blunting of the ERN after acute alcohol were more likely to return to more moderate drinking patterns. These results suggest that cues signalling reward opportunities might activate a go-response mode and larger N2 (detection of increased conflict) for these cues might be necessary for inhibition. The ERN results suggest a deficiency in the monitoring system for alcohol cues. Finally, a lack of alcohol-induced deterioration of error monitoring for cues with high salience might be a vulnerability factor for alcohol abuse in adolescents.

SUBMITTER: Korucuoglu O

PROVIDER: S-EPMC4289948 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature

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Alcohol-induced changes in conflict monitoring and error detection as predictors of alcohol use in late adolescence.

Korucuoglu Ozlem O Gladwin Thomas E TE Wiers Reinout W RW

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20140820 3

Adolescence is a vulnerable period for the development of substance use and related problems. Understanding how exposure to drugs influences the adolescent brain could reveal mechanisms underlying risk for addiction later in life. In the current study, 87 adolescents (16-20-year olds; the local legal drinking age was16, allowing the inclusion of younger subjects than usually possible) underwent EEG measurements during a Go/No-Go task with and without alcohol cues; after placebo and a low dose of ...[more]

PMID: 25189856

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Project description:BackgroundThe link between parental monitoring and adolescent alcohol use is well established, but the directionality of this relationship is somewhat elusive. The literature suggests that parental engagement serves a protective function with respect to alcohol use, but that parental monitoring may also diminish in response to recurrent risk behavior. The lower rate of alcohol use despite evidence of lower levels of parental monitoring in Black versus White youth raises the question of for whom and under what conditions parental monitoring and alcohol use are associated.MethodsData were drawn from a community sample of 1,634 female adolescents (954 Black, 680 White) from 4 age cohorts, assessed annually in an accelerated longitudinal design. This study uses data spanning ages 12 to 17; parental monitoring and alcohol use were assessed via self-report, while demographic and adolescent psychosocial risk factors were derived from parent reports when the girls were age 12. An autoregressive cross-lagged panel mixture model was used to identify discrete patterns of parental monitoring and alcohol use associations across adolescence, and psychosocial factors that differentiate between them.ResultsTwo discrete patterns of codeveloping alcohol use and parental monitoring emerged: one with stable bidirectional and autoregressive links (79%) and another differing from the majority profile in terms of the absence (alcohol use to parental monitoring) and direction (parental monitoring to alcohol use) of cross-construct influences (21%). Those in the minority profile were, at age 12, more likely to have received public assistance, resided in single-parent households, reached puberty, and manifest more severe conduct problems.ConclusionsIdentifying subgroups of girls with distinct patterns of codeveloping alcohol use and parental monitoring is particularly relevant to the development and implementation of family-level interventions, both in terms of targeting those with known demographic risk factors, and tailoring programs to address behavioral correlates, such as conduct problems.

Dataset Information

Alcohol-induced changes in conflict monitoring and error detection as predictors of alcohol use in late adolescence.

Publications

Alcohol-induced changes in conflict monitoring and error detection as predictors of alcohol use in late adolescence.

Similar Datasets

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