Ontology highlight
ABSTRACT:
SUBMITTER: Jeff JM
PROVIDER: S-EPMC4290789 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Jeff Janina M JM Brown-Gentry Kristin K Goodloe Robert R Ritchie Marylyn D MD Denny Joshua C JC Kho Abel N AN Armstrong Loren L LL McClellan Bob B Mayo Ping P Allen Melissa M Jin Hailing H Gillani Niloufar B NB Schnetz-Boutaud Nathalie N Dilks Holli H HH Basford Melissa A MA Pacheco Jennifer A JA Jarvik Gail P GP Chisholm Rex L RL Roden Dan M DM Hayes M Geoffrey MG Crawford Dana C DC
Evolutionary computation, machine learning and data mining in bioinformatics. EvoBIO (Conference) 20140101
The NAv1.5 sodium channel α subunit is the predominant α-subunit expressed in the heart and is associated with cardiac arrhythmias. We tested five previously identified <i>SCN5A</i> variants (rs7374138, rs7637849, rs7637849, rs7629265, and rs11129796) for an association with PR interval and QRS duration in two unique study populations: the Third National Health and Nutrition Examination Survey (NHANES III, n= 552) accessed by the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) ...[more]