Ontology highlight
ABSTRACT:
SUBMITTER: Bobrov AG
PROVIDER: S-EPMC4295937 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Bobrov Alexander G AG Kirillina Olga O Vadyvaloo Viveka V Koestler Benjamin J BJ Hinz Angela K AK Mack Dietrich D Waters Christopher M CM Perry Robert D RD
Environmental microbiology 20140311 4
The second messenger molecule cyclic diguanylate is essential for Yersinia pestis biofilm formation that is important for blockage-dependent plague transmission from fleas to mammals. Two diguanylate cyclases (DGCs) HmsT and Y3730 (HmsD) are responsible for biofilm formation in vitro and biofilm-dependent blockage in the oriental rat flea Xenopsylla cheopis respectively. Here, we have identified a tripartite signalling system encoded by the y3729-y3731 operon that is responsible for regulation o ...[more]