Ontology highlight
ABSTRACT:
SUBMITTER: Ponimaskin E
PROVIDER: S-EPMC4301590 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Ponimaskin Evgeni E Dityateva Galina G Ruonala Mika O MO Fukata Masaki M Fukata Yuko Y Kobe Fritz F Wouters Fred S FS Delling Markus M Bredt David S DS Schachner Melitta M Dityatev Alexander A
The Journal of neuroscience : the official journal of the Society for Neuroscience 20080901 36
During development of the nervous system, short- and long-range signals cooperate to promote axonal growth, guidance, and target innervation. Particularly, a short-range signal transducer, the neural cell adhesion molecule (NCAM), stimulates neurite outgrowth via mechanisms that require posttranslational modification of NCAM and signaling via receptors to a long-range messenger, the fibroblast growth factor (FGF). In the present study we further characterized a mechanism which regulates the func ...[more]