Ontology highlight
ABSTRACT:
SUBMITTER: Pathak RU
PROVIDER: S-EPMC4301625 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Pathak Rashmi U RU Srinivasan Arumugam A Mishra Rakesh K RK
BMC genomics 20141125
<h4>Background</h4>Eukaryotic genome acquires functionality upon proper packaging within the nucleus. This process is facilitated by the structural framework of Nuclear Matrix, a nucleo-proteinaceous meshwork. Matrix Attachment Regions (MARs) in the genome serve as anchoring sites to this framework.<h4>Results</h4>Here we report direct sequencing of the MAR preparation from Drosophila melanogaster embryos and identify >7350 MARs. This amounts to ~2.5% of the fly genome and often coincide with AT ...[more]