Ontology highlight
ABSTRACT:
SUBMITTER: Grant SG
PROVIDER: S-EPMC4301735 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Grant Stephen G SG Melan Melissa A MA Latimer Jean J JJ Witt-Enderby Paula A PA
Expert reviews in molecular medicine 20090205
Recent studies have suggested that the pineal hormone melatonin may protect against breast cancer, and the mechanisms underlying its actions are becoming clearer. Melatonin works through receptors and distinct second messenger pathways to reduce cellular proliferation and to induce cellular differentiation. In addition, independently of receptors melatonin can modulate oestrogen-dependent pathways and reduce free-radical formation, thus preventing mutation and cellular toxicity. The fact that me ...[more]