Ontology highlight
ABSTRACT:
SUBMITTER: Reimers LL
PROVIDER: S-EPMC4302042 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Reimers Laura L LL Crew Katherine D KD Bradshaw Patrick T PT Santella Regina M RM Steck Susan E SE Sirosh Iryna I Terry Mary Beth MB Hershman Dawn L DL Shane Elizabeth E Cremers Serge S Dworakowski Elzbieta E Teitelbaum Susan L SL Neugut Alfred I AI Gammon Marilie D MD
Cancer causes & control : CCC 20141125 2
<h4>Purpose</h4>Studies of vitamin D-pathway genetic variants in relation to cancer risk have been inconsistent. We examined the associations between vitamin D-related genetic polymorphisms, plasma 25-hydroxyvitamin D [25(OH)D], and breast cancer risk.<h4>Methods</h4>In a population-based case-control study of 967 incident breast cancer cases and 993 controls, we genotyped 25 polymorphisms encoding the vitamin D receptor (VDR) gene, 1α-hydroxylase (CYP27B1), 24-hydroxylase (CYP24A1), and vitamin ...[more]