Ontology highlight
ABSTRACT:
SUBMITTER: Yuan T
PROVIDER: S-EPMC4302205 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Yuan Tianyi T Lu Jingze J Zhang Jinzhong J Zhang Yongdeng Y Chen Liangyi L
Biophysical journal 20150101 2
Total internal reflection fluorescence microscope has often been used to study the molecular mechanisms underlying vesicle exocytosis. However, the spatial occurrence of the fusion events within a single cell is not frequently explored due to the lack of sensitive and accurate computer-assisted programs to analyze large image data sets. Here, we have developed an image analysis platform for the nonbiased identification of different types of vesicle fusion events with high accuracy in different c ...[more]