Ontology highlight
ABSTRACT:
SUBMITTER: Murphy EA
PROVIDER: S-EPMC4305449 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Murphy Elizabeth A EA Roddey John Cooper JC McEvoy Linda K LK Holland Dominic D Hagler D J DJ Dale Anders M AM Brewer James B JB
Brain imaging and behavior 20120301 1
Two alleles in cholesteryl ester transfer protein (CETP) gene polymorphisms have been disputably linked to enhanced cognition and decreased risk of Alzheimer's disease (AD): the V and A alleles of I405V and C-629A. This study investigates whether these polymorphisms affect brain structure in 188 elderly controls and 318 AD or mild cognitive impairment (MCI) subjects from the Alzheimer's Disease Neuroimaging Initiative cohort. Nominally signficant associations were dependent on APOE ε4 carrier st ...[more]